Cannabis-based medicines for chronic pain management: current and future prospects

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The medicinal use of cannabis has recently become the focus of much medical, as well as political, attention. The endocannabinoid system is undoubtedly a new and exciting pharmaceutical target for chronic pain management, but transition from preclinical to clinical studies has so far proved difficult. Although it is reasonable to consider cannabinoids for otherwise unresponsive pain, care should be taken in frail clinical populations. As this has become a socioeconomic and political issue in which agendas often take precedence over due diligence, there is a pressing need for unbiased empirical data and high quality evidence to better inform prescribers and patients.

Democrat Pete Buttigieg used marijuana ‘a handful of times’

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Pete Buttigieg, speaking to reporters after touring a legal pot dispensary in suburban Las Vegas, was asked about whether he’d ever used marijuana.
Perhaps some of the blame for this lies with the man who, a century ago, was probably the most famous economist in the world – Irving Fisher.

It was Fisher who notoriously claimed, in October 1929, the stock market had reached “a permanently high plateau”.

US Veterinarians’ Knowledge, Experience, and Perception Regarding the Use of Cannabidiol for Canine Medical Conditions

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Due to the myriad of laws concerning cannabis, there is little empirical research regarding the veterinary use of cannabidiol (CBD). This study used the Veterinary Information Network (VIN) to gauge US veterinarians’ knowledge level, views and experiences related to the use of cannabinoids in the medical treatment of dogs. Overall, CBD was most frequently discussed as a potential treatment for pain management, anxiety and seizures.

What prohibition’s failure means for the legalisation of cannabis

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Economists have a bit of an image problem. People think we shamelessly massage statistics, overconfidently make terrible predictions, and are no fun at drinks parties.

Perhaps some of the blame for this lies with the man who, a century ago, was probably the most famous economist in the world – Irving Fisher.

It was Fisher who notoriously claimed, in October 1929, the stock market had reached “a permanently high plateau”.

Perspectives on cannabis as a substitute for opioid analgesics

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With the opioid epidemic reaching new heights in the USA, it has become critical to find suitable alternatives to opioids. Cannabis, an antinociceptive, is a strong contender to help patients reduce their opioid usage. A growing literature has been examining the complex effects cannabis has on pain relief and on opioid usage; whether it is a substitute for opioids or increases their use.

Perceived Efficacy of Medical Cannabis in the Treatment of Co-Occurring Health-Related Quality of Life Symptoms

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For persons living with chronic conditions, health-related quality of life (HRQoL) symptoms, such as pain, anxiety, depression, and insomnia, often interact and mutually reinforce one another. There is evidence that medical cannabis (MC) may be efficacious in ameliorating such symptoms and improving HRQoL. As many of these HRQoL symptoms may mutually reinforce one another, we conducted an exploratory study to investigate how MC users perceive the efficacy of MC in addressing co-occurring HRQoL symptoms. Our results suggest that co-occurring pain, anxiety, and depression may be particularly amenable to treatment with MC.

Therapeutic potential of medicinal marijuana: an educational primer for health care professionals

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This review is particularly important for primary care physicians whose patients may be interested in using as an alternative therapy. In response to increased interest in medicinal marijuana (MM), Health Canada released a document in 2013 for general practitioners (GPs) as an educational tool on the efficacy of MM in treating some chronic and acute conditions. The purpose of this paper is to offer physicians an educational tool that provides a necessary, evidence-based analysis of the therapeutic potential of MM and to ensure physicians are making decisions on the therapeutic use of MM in good faith.