Cannabidiol Induces Cell Cycle Arrest and Cell Apoptosis in Human Gastric Cancer SGC-7901 Cells

The main chemical component of cannabis, cannabidiol (CBD), has been shown to have antitumor properties. The present study examined the in vitro effects of CBD on human gastric cancer SGC-7901 cells. We found that CBD significantly inhibited the proliferation and colony formation of SGC-7901 cells. These results indicated that CBD could induce G0-G1 phase cell cycle arrest and apoptosis by increasing ROS production, leading to the inhibition of SGC-7901 cell proliferation, thereby suggesting that CBD may have therapeutic effects on gastric cancer.

CanEx Jamaica

This year we are pulling out all the stops to deliver a conference experience par excellence here in Montego Bay Jamaica. You can expect incredible content (90+ experts), unsurpassed networking, global perspectives and information and (shhh…..fantastic entertainment)….and did we mention that it’s in Jamaica?

Patient Counseling Guidelines for the Use of Cannabis for the Treatment of Chemotherapy-Induced Nausea/Vomiting and Chronic Pain

The use of cannabis medications has grown in recent years for the symptomatic relief of chemotherapy-induced nausea/vomiting (CINV) and chronic pain (cancer-related and non-cancer-related). As states legalize the use of cannabis, it is important for pharmacists and other health care professionals to be aware of how to counsel patients receiving prescriptions for cannabis medications.

Attitudes and Beliefs About Medical Usefulness and Legalization of Marijuana among Cancer Patients in a Legalized and a Nonlegalized State

There is a growing preference for the use of marijuana for medical purposes, despite limited evidence regarding its benefits and potential safety risks. Legalization status may play a role in the attitudes and preferences toward medical marijuana (MM). Adult cancer patients seen by the Palliative Care teams in the outpatient centers were evaluated. Cancer patients from both legalized and nonlegalized states supported legalization of marijuana for medical purposes and believed in its medical use. The support for legalization for medical use was significantly higher than for recreational use in both states.

Opportunities for cannabis in supportive care in cancer

Cannabis has the potential to modulate some of the most common and debilitating symptoms of cancer and its treatments, including nausea and vomiting, loss of appetite, and pain. Cannabis has multifaceted potential bioactive benefits that appear to outweigh its risks in many situations. Further research is required to elucidate its mechanisms of action and efficacy and to optimize cannabis preparations and doses for specific populations affected by cancer.

Out of the darkness by PSY-23

For too many people the reality of an addiction can become a deeper and darker void than we feel able to escape from and, regardless of their best intentions, what begins as a search for peace can end up as a fight for survival. Recently, I was contacted by Rich who wanted to talk about his experiences with cannabis over the years. He had been an old-school smuggler with connections to Morocco (amongst other places) who seemed to have an endless array of anecdotes and tales of adventure which he thought might be of interest to our readers. After a couple of emails and phone calls, I set out to meet with him to find out more.