Cannabinoids in Pediatrics

Despite its controversial nature, the use of medical marijuana and cannabis-derived medicinal products grows more popular with each passing year. As of November 2016, over 40 states have passed legislation regarding the use of either medical marijuana or cannabidiol products. This review will deliver the history of marijuana use and legislation in the United States in addition to the currently available medical literature to equip pediatric health care providers with resources to provide patients and their parents the best recommendation for safe and appropriate use of cannabis-containing compounds.

Short-Term Efficacy of CBD-Enriched Hemp Oil in Girls with Dysautonomic Syndrome after Human Papillomavirus Vaccination

Cannabidiol (CBD)-based treatments for several diseases, including Tourette’s syndrome, multiple sclerosis, epilepsy, movement disorders and glaucoma, are proving to be beneficial and the scientific clinical background of the drug is continuously evolving. This study demonstrated the safety and tolerability of CBD-rich hemp oil and the primary efficacy endpoint. Randomized controlled trials are warranted to characterize the safety profile and efficacy of this compound.

Colorado Researchers Looking For Dogs To Test CBD Treatments

Research in Colorado is progressing into the four legged variety Researchers at Colorado State University are looking for dogs with osteoarthritis or epilepsy to test cannabidiol treatments. Cannabidiols, or CBDs, are a non-psychoactive component of marijuana. “The CBD product is very low in the psychoactive component of cannabis, THC, making it safe for use in dogs,” researchers stated on the CSU website. Each dog will be randomly assigned…

Efficacy and safety of cannabis for treating children with refractory epilepsy

The aim of this literature review was to examine the evidence base for the safety and efficacy of cannabis in treating children with refractory epilepsy.  Cannabis may reduce seizures in some children and young people with refractory epilepsy, however, its success may be affected by aetiology of the epilepsy or concomitant anti-epileptic drug use, and a therapeutic dose has not been found. Positive side effects were also found including improved sleep, alertness and mood.

Pharmacology of cannabinoids in the treatment of epilepsy

The use of cannabis products in the treatment of epilepsy has long been of interest to researchers and clinicians alike; however, until recently very little published data were available to support its use. As cannabinoids and cannabis-based products are studied for efficacy as anticonvulsants, more investigation is needed regarding the specific targets of action, optimal drug delivery, and potential drug-drug interactions. This article is part of a Special Issue titled Cannabinoids and Epilepsy.

Medical Cannabinoids in Children and Adolescents: A Systematic Review

Legalization of medical marijuana in many states has led to a widening gap between the accessibility and the evidence for cannabinoids as a medical treatment. Evidence for benefit was strongest for chemotherapy-induced nausea and vomiting, with increasing evidence of benefit for epilepsy. At this time, there is insufficient evidence to support use for spasticity, neuropathic pain, post-traumatic stress disorder, and Tourette syndrome. Additional research is needed to evaluate the potential role of medical cannabinoids in children and adolescents

Marijuana Can Help Children with Seizures, Cancer Nausea

Researchers said medical marijuana is effective in treating some conditions in children, but they urge caution on using the drug in young patients. Should kids and adolescents ever use medical marijuana? Administering the drug to younger patients remains somewhat contentious, but it also appears effective in treating a limited number of symptoms. According to a new…