God of War – PS4 (18)

A New Beginning – His vengeance against the gods of Olympus far behind him, Kratos now lives as a man in the lands of Norse Gods and monsters. It is in this harsh, unforgiving world that he must fight to survive… and teach his son to do the same Second Chances As mentor and protector…

Endocannabinoid system acts as a regulator of immune homeostasis in the gut

Endogenous cannabinoids (endocannabinoids) are small molecules biosynthesized from membrane glycerophospholipid. Anandamide (AEA) is an endogenous intestinal cannabinoid that controls appetite and energy balance by engagement of the enteric nervous system through cannabinoid receptors. Our study unveils a role for the endocannabinoid system in maintaining immune homeostasis in the gut/pancreas and reveals a conversation between the nervous and immune systems using distinct receptors.