Modulating the endocannabinoid pathway as treatment for peripheral neuropathic pain: a selected review of preclinical studies

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Chemotherapy-induced neuropathic pain is a distressing and commonly occurring side effect of many commonly used chemotherapeutic agents, which in some cases may prevent cancer patients from being able to complete their treatment. Cannabinoid based therapies have the potential to manage or even prevent pain associated with this syndrome. These studies also provide in-sight into the biological mechanism behind the therapeutic utility of cannabis compounds in managing chemotherapy-induced neuropathic pain, and provide a basis for the conduct of future clinical studies in patients of this population.

Danish companies queue to grow cannabis

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Companies have begun applying to Denmark’s medicines regulator to grow cannabis plants ahead of the drug becoming legalised for medicinal purposes next year, it’s reported. Some 13 companies have already submitted applications for growing cannabis plants to the Laegemiddelstyrelsen, so that they can help treat Danes suffering from painful illnesses such as cancer and multiple…

Medical Cannabinoids in Children and Adolescents: A Systematic Review

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Legalization of medical marijuana in many states has led to a widening gap between the accessibility and the evidence for cannabinoids as a medical treatment. Evidence for benefit was strongest for chemotherapy-induced nausea and vomiting, with increasing evidence of benefit for epilepsy. At this time, there is insufficient evidence to support use for spasticity, neuropathic pain, post-traumatic stress disorder, and Tourette syndrome. Additional research is needed to evaluate the potential role of medical cannabinoids in children and adolescents

Marijuana Can Help Children with Seizures, Cancer Nausea

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Researchers said medical marijuana is effective in treating some conditions in children, but they urge caution on using the drug in young patients. Should kids and adolescents ever use medical marijuana? Administering the drug to younger patients remains somewhat contentious, but it also appears effective in treating a limited number of symptoms. According to a new…

Review study finds limited data on medical cannabis use in children

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A systematic review of published studies on the use of medical cannabis in children and adolescents finds a notable lack of studies and a minimal number of the randomized, controlled trials needed to confirm the effectiveness of a treatment In their paper published in the journal Pediatrics, Massachusetts General Hospital (MGH) investigators Shane Shucheng Wong, MD,…

‘Right to Try’ and Proving and Disproving Medical Marijuana Claims by the FDA

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There are only a handful of medical marijuana or CBD-related clinical trials Recent statements from the Federal Drug Administration Commissioner suggest that the agency may be considering the legitimacy of medical marijuana claims, years after legalization of the herb for medicinal purposes has taken hold in over half of the country. Most specifically, the concern…

Quarter of Seattle cancer patients turn to marijuana to help cope with pain, stress and nausea

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Doctor warns taking cannabis while being treated for cancer could be dangerous by Ian Johnston Nearly a quarter of cancer patients had used cannabis in the past year to help cope with symptoms including physical pain, nausea and depression, according to a new study in the US. Researchers surveyed 926 patients at the Seattle Cancer…