Canada – Kamloops council approves 23rd cannabis store
City council has approved a 23rd cannabis retailer for Kamloops, which is set to open in the Dallas area.
Exogenous Cannabinoid Efficacy: Merely a Pharmacokinetic Interaction?
Endocannabinoid pharmacology is now relatively well understood with a number of endocannabinoids and endogenous cannabinoid neurotransmitters identified and the pharmacokinetics relatively well ascertained. Endogenous cannabinoids have been shown to have key roles in immune and pain pathways and neuro-behavioural signalling including appetite regulation. Significant recent interest has thus been shown in understanding these pathways to guide the development of agents that inhibit the natural catabolism of endogenous cannabinoids to modify pain and appetite, and to synthesise antagonists for the treatment of disease such as obesity.
