Colorado girl sues Jeff Sessions to legalize medical marijuana nationwide

A Colorado girl who suffers from seizures joined a lawsuit to sue U.S. Attorney General Jeff Sessions in a bid to legalize medical marijuana nationwide. Alexis Bortell, 12, told FOX31 Denver she was diagnosed with epilepsy and traditional medicine wasn’t helping her seizures. Her doctors in Texas recommended an invasive brain surgery, but a pediatrician suggested medical…

Selective activation of cannabinoid receptor-2 reduces neuroinflammation after traumatic brain injury via alternative macrophage polarization

Inflammation is an important mediator of secondary neurological injury after traumatic brain injury (TBI). Endocannabinoids, endogenously produced arachidonate based lipids, have recently emerged as powerful anti-inflammatory compounds, yet the molecular and cellular mechanisms underlying these effects are poorly defined. Endocannabinoids are physiological ligands for two known cannabinoid receptors, CB1R and CB2R. In the present study, we hypothesized that selective activation of CB2R attenuates neuroinflammation and reduces neurovascular injury after TBI.

Efficacy and safety of cannabis for treating children with refractory epilepsy

The aim of this literature review was to examine the evidence base for the safety and efficacy of cannabis in treating children with refractory epilepsy.  Cannabis may reduce seizures in some children and young people with refractory epilepsy, however, its success may be affected by aetiology of the epilepsy or concomitant anti-epileptic drug use, and a therapeutic dose has not been found. Positive side effects were also found including improved sleep, alertness and mood.

World’s Oldest Cannabis Seed Bank Honours 73 year French activist with own variety

Dutch company Sensi Seeds, the world’s oldest and most respected cannabis seed bank, pays official homage to Michka Seeliger-Chatelain with their latest sativa seed strain MichkaÒ. World’s Oldest Cannabis Seed Bank Honours 73 year French activist with own variety   Through her significant impact in in the cannabis community, Michka, has become known as the…